Association of FCγRIIA (CD32) polymorphism with susceptibility to brucellosis

association of fcγriia (cd32) polymorphism with susceptibility to brucellosis

background: brucellosis is the major bacterial zoonoses of global importance caused by brucella spps. fcγriia receptor plays a central role in phagocytosis of igg2-opsonized bacteria. fcγriia exhibits allelic polymorphisms with different capacities for binding igg2 and phagocytosis. cells expressing fc γ riia-h131, bind more efficiently to complexes of igg2 than those expressing the fc γ rii a ...

Association of Apolipoprotein E Polymorphism with Susceptibility to Multiple Sclerosis

Association of human Fc gamma RIIa (CD32) polymorphism with susceptibility to and severity of meningococcal disease.

Phagocytosis of bacteria constitutes an important defense mechanism against invasive bacterial diseases. Efficacy of phagocytosis by polymorphonuclear neutrophils is known to vary between allotypes of Fc gamma RIIa (a class of Fc receptors for immunoglobulins that is constitutively expressed on neutrophils). We compared the distribution of Fc gamma RIIa-R131 and Fc gamma RIIa-H131 allotypes in ...

IL-33 polymorphism rs1929992 and its association with susceptibility to different pattern of multiple sclerosis

Background: Multiple sclerosis is the most common autoimmune demyelinating disease of the central nervous system (CNS). Interleukin-33 (IL-33) is a cytokine with both pro-inflammatory and anti-inflammatory activities that implicated in the pathogenesis of some autoimmune diseases. The aim of this study was to determine single nucleotide polymorphism (SNP) of IL-33, rs1929992, in patient’s gene ...

Association of tumor necrosis factor–α-308 (G→A) polymorphism and susceptibility to brucellosis

Jafari-Shakib Reza, Rafiei Alireza, Ansari Mostafa, Khalilian Alireza, Hajilooi Mehrdad Department of Immunology and Microbiology, Rasht Medical School, Guilan University of Medical Sciences, Rasht; Cellular and Molecular Biology Research Center, Sari Medical School, Mazandaran University of Medical Sciences, Sari; Department of Internal Medicine, Ekbatan Hospital, Medical School, University of...

the study of aaag repeat polymorphism in promoter of errg gene and its association with the risk of breast cancer in isfahan region

چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...